PPIC, EMP3 and CHI3L1 Are Novel Prognostic Markers for High Grade Glioma
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چکیده
منابع مشابه
PPIC, EMP3 and CHI3L1 Are Novel Prognostic Markers for High Grade Glioma
Current treatment methods for patients diagnosed with gliomas have shown limited success. This is partly due to the lack of prognostic genes available to accurately predict disease outcomes. The aim of this study was to investigate novel prognostic genes based on the molecular profile of tumor samples and their correlation with clinical parameters. In the current study, microarray data (GSE4412...
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We evaluated the prognostic and predictive value of a range of molecular changes in the setting of a randomised trial comparing standard PCV (procarbazine, CCNU (1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea) and vincristine) chemotherapy with the standard temozolomide (TMZ) 5-day (200 mg/m2/day) schedule and a 21-day (100 mg/m2/day) schedule in chemo-naïve, high-grade glioma (non-oligodendrogli...
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OBJECTIVE The purpose of this study was to perform a survival analysis of patients with high-grade multicentric gliomas and to assess the influence of various prognostic factors on overall survival (OS). METHODS A literature search on PubMed and Web of Science was performed for literature in English published from 1880 to October 2017. Detailed information including demographics, clinical cha...
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BACKGROUND High grade glioma (HGG) is an aggressive form of brain cancer. Treatment of HGG usually entails biopsy, or resection if safe, followed by radiotherapy. Temozolomide is a novel oral chemotherapy drug that penetrates into the brain and purportedly has a low incidence of adverse events. OBJECTIVES To assess whether temozolomide has any advantage for treating HGG in either primary or r...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2016
ISSN: 1422-0067
DOI: 10.3390/ijms17111808